for only opening the windows; and now we won’t let a consumptive patient have as much as a roof over his head. Oh, it’s very very interesting to an old man.
Ridgeon
You old cynic, you don’t believe a bit in my discovery.
Sir Patrick
No, no: I don’t go quite so far as that, Colly. But still, you remember Jane Marsh?
Ridgeon
Jane Marsh? No.
Sir Patrick
You don’t!
Ridgeon
No.
Sir Patrick
You mean to tell me you don’t remember the woman with the tuberculosis ulcer on her arm?
Ridgeon
Enlightened. Oh, your washerwoman’s daughter. Was her name Jane Marsh? I forgot.
Sir Patrick
Perhaps you’ve forgotten also that you undertook to cure her with Koch’s tuberculin.
Ridgeon
And instead of curing her, it rotted her arm right off. Yes: I remember. Poor Jane! However, she makes a good living out of that arm now by showing it at medical lectures.
Sir Patrick
Still, that wasn’t quite what you intended, was it?
Ridgeon
I took my chance of it.
Sir Patrick
Jane did, you mean.
Ridgeon
Well, it’s always the patient who has to take the chance when an experiment is necessary. And we can find out nothing without experiment.
Sir Patrick
What did you find out from Jane’s case?
Ridgeon
I found out that the inoculation that ought to cure sometimes kills.
Sir Patrick
I could have told you that. I’ve tried these modern inoculations a bit myself. I’ve killed people with them; and I’ve cured people with them; but I gave them up because I never could tell which I was going to do.
Ridgeon
Taking a pamphlet from a drawer in the writing-table and handing it to him. Read that the next time you have an hour to spare; and you’ll find out why.
Sir Patrick
Grumbling and fumbling for his spectacles. Oh, bother your pamphlets. What’s the practice of it? Looking at the pamphlet. Opsonin? What the devil is opsonin?
Ridgeon
Opsonin is what you butter the disease germs with to make your white blood corpuscles eat them. He sits down again on the couch.
Sir Patrick
That’s not new. I’ve heard this notion that the white corpuscles—what is it that what’s his name?—Metchnikoff—calls them?
Ridgeon
Phagocytes.
Sir Patrick
Aye, phagocytes: yes, yes, yes. Well, I heard this theory that the phagocytes eat up the disease germs years ago: long before you came into fashion. Besides, they don’t always eat them.
Ridgeon
They do when you butter them with opsonin.
Sir Patrick
Gammon.
Ridgeon
No: it’s not gammon. What it comes to in practice is this. The phagocytes won’t eat the microbes unless the microbes are nicely buttered for them. Well, the patient manufactures the butter for himself all right; but my discovery is that the manufacture of that butter, which I call opsonin, goes on in the system by ups and downs—Nature being always rhythmical, you know—and that what the inoculation does is to stimulate the ups or downs, as the case may be. If we had inoculated Jane Marsh when her butter factory was on the upgrade, we should have cured her arm. But we got in on the downgrade and lost her arm for her. I call the upgrade the positive phase and the downgrade the negative phase. Everything depends on your inoculating at the right moment. Inoculate when the patient is in the negative phase and you kill: inoculate when the patient is in the positive phase and you cure.
Sir Patrick
And pray how are you to know whether the patient is in the positive or the negative phase?
Ridgeon
Send a drop of the patient’s blood to the laboratory at St. Anne’s; and in fifteen minutes I’ll give you his opsonin index in figures. If the figure is one, inoculate and cure: if it’s under point eight, inoculate and kill. That’s my discovery: the most important that has been made since Harvey discovered the circulation of the blood. My tuberculosis patients don’t die now.
Sir Patrick
And mine do when my inoculation catches them in the negative phase, as you call it. Eh?
Ridgeon
Precisely. To inject a vaccine into a patient without first testing his opsonin is as near murder as a respectable practitioner can get. If I wanted to kill a man I should kill him that way.
Emmy
Looking in. Will you see a lady that wants her husband’s lungs cured?
Ridgeon
Impatiently. No. Haven’t I told you I will see nobody? To Sir Patrick. I live in a state of siege ever since it got about that I’m a magician who can cure consumption with a drop of serum. To Emmy. Don’t come to me again about people who have no appointments. I tell you I can see nobody.
Emmy
Well, I’ll tell her to wait a bit.
Ridgeon
Furious. You’ll tell her I can’t see her, and send her away: do you hear?
Emmy
Unmoved. Well, will you see Mr. Cutler Walpole? He don’t want a cure: he only wants to congratulate you.
Ridgeon
Of course. Show him up. She turns to go. Stop. To Sir Patrick. I want two minutes more with you between ourselves. To Emmy. Emmy: ask Mr. Walpole to wait just two minutes, while I finish a consultation.
Emmy
Oh, he’ll wait all right. He’s talking to the poor lady. She goes out.
Sir Patrick
Well? what is it?
Ridgeon
Don’t laugh at me. I want your advice.
Sir Patrick
Professional advice?
Ridgeon
Yes. There’s something the matter with me. I don’t know what it is.
Sir Patrick
Neither do I. I suppose you’ve been sounded.
Ridgeon
Yes, of course. There’s nothing wrong with any of the organs: nothing special, anyhow. But I have a curious aching: I don’t know where: I can’t localize it. Sometimes I think it’s my heart: sometimes I suspect my spine. It doesn’t exactly hurt me; but it unsettles me completely. I feel that something is going to happen. And there are other symptoms. Scraps of tunes come into my head that seem to me very pretty, though they’re quite commonplace.
Sir Patrick
Do you hear voices?
Ridgeon
No.
Sir
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