As a young man, Domaradsky had admired the heroic workers of the anti-plague institutes, who protected the public from scourge. Now, the same institutes were quietly dragged into the search for agents of killing. According to Domaradsky, the “Problem No. 5” for civil defense became a cover story for weapons work. The institutes were asked to gather dangerous pathogens they found on the steppe, and to study what made them virulent, so they could be fed into the Biopreparat flasks.

The Biological Weapons Convention entered into force on March 26, 1975. That June, Alexei A. Roshchin, the Soviet ambassador to the disarmament committee in Geneva, declared: “At the present time, the Soviet Union does not have in its possession any bacteriological (biological) agents or toxins, weapons, equipment or means of delivery specified in Article 1 of the Convention.”13

Whether Roshchin was aware of the reality is unknown, but Domaradsky certainly knew the truth. “I knew that I was part of a system that was out of control, but I could not think of an alternative way to live my life,” Domaradsky reflected later. “Like my colleagues, I faced a terrible choice: remain with a corrupt and non- functioning system, doing work of (at best) a certain moral ambiguity, or sacrifice my entire scientific career.”

———

Soon after the biological weapons treaty was ratified, U.S. intelligence satellites picked up signs of unusual new factories being built in the Soviet Union. William Beecher, the military correspondent of the Boston Globe, reported that satellites detected six potential biological warfare facilities. The plants “feature extremely high smokestacks and refrigerated storage bunkers associated with germ warfare production,” Beecher wrote.14

Then in April 1979 came the Sverdlovsk anthrax epidemic. Fragmentary reports began to reach the West. The intelligence community had long suspected a secret Soviet biological weapons program existed. Now perhaps there was evidence.

The first reports began filtering into the U.S. Central Intelligence Agency through Soviet emigres. A top- secret CIA intelligence report on October 15, 1979, cited an unnamed Soviet emigre as saying that three close friends had told him in May “of an accident at a biological warfare (BW) institute in Sverdlovsk which resulted in 40 to 60 deaths. Other sources have also heard rumors of such an accident.” The report was vague, but noted there was “a suspect BW installation in Sverdlovsk” and that “two reports of the accident suggested a disease that also affects cattle, and one source identified the bacterial agent anthrax as a possible cause.”15

In December, Soviet forces invaded Afghanistan. The SALT II treaty was endangered. If the Soviets were found to have violated the five-year-old biological weapons treaty, it would be yet another serious setback to ratification of the nuclear arms agreement.

Unexpectedly, fresh intelligence arrived in Washington about Sverdlovsk. A secret CIA report on January 28, 1980, said: “Recent intelligence strengthens allegations that an accident at a BW installation caused civilian casualties in southern Sverdlovsk during April 1979.” This report added the claim of a possible explosion at the plant that caused the release. The report said that “pathogenic bacteria allegedly escaped into the air and spread over industrial and residential areas of southern Sverdlovsk.” The report also took note that, “An announcement about an anthrax epidemic in a public health context appears to have been designed to prevent a possible panic among Sverdlovsk’s million-plus population. The magnitude of the epidemic and the causative organism remain conjecture.”

In January and February 1980, a practicing surgeon from a Sverdlovsk hospital gave U.S. intelligence agencies a new and more detailed account, which the Defense Intelligence Agency described in a top-secret report March 3. Although some details were vague, the surgeon was correct about many specifics. He said the accident occurred inside a military installation where “dispersible biological weapons” were produced. He said that in April 1979 there had been a “loud explosion which was attributed to a jet aircraft”—this later turned out to be an error —and he noted that within four days, victims had been arriving at Hospital No. 20.

He also recounted the symptoms of the victims, the deaths of workers at the ceramics factory, the decision to send patients to hospital No. 40 and the announcement that tainted meat caused the outbreak. He added, “This explanation was not accepted by the doctors in attendance because the fatalities were caused by the pulmonary type of anthrax as opposed to the gastric or skin anthrax which would be more likely if one had eaten or handled contaminated beef.” The intelligence agency concluded in the report that the information “presents a very strong circumstantial case for biological weapons activity” at the facility.

In Moscow on Monday, March 17, 1980, the U.S. ambassador, Thomas Watson, raised the Sverdlovsk anthrax epidemic in a quiet inquiry with the Soviet Foreign Ministry.16 The ministry did not respond right away. In Washington on Tuesday, March 18, a State Department spokesman, responding to questions from journalists, read out a public statement saying there were “disturbing indications” that “a lethal biological agent” might have hit Sverdlovsk in 1979 and this had raised questions “about whether such material was present in quantities consistent with” the biological weapons treaty. The Soviets were surprised by the State Department’s public announcement, which they hadn’t expected.17 The Soviet response came on Thursday, March 20, that the outbreak was caused by contaminated meat.18 The issue was extremely sensitive because that same week in Geneva, diplomats from fifty-three countries were winding up the first five-year review conference of the Biological Weapons Convention. They were on the verge of approving a final declaration. The U.S. ambassador to the talks, Charles Flowerree, told his Soviet counterpart, Victor Israelyan, about the message of concern over Sverdlovsk delivered in Moscow.

The Soviets decided to keep stonewalling. On Friday, March 21, acting on instructions from Moscow, Israelyan made a public statement to the conference. He reassured the conference there was nothing to worry about. “There are no grounds whatsoever” for the questions raised by the United States, he said. “In March–April 1979 in the area of Sverdlovsk there did in fact occur an ordinary outbreak of anthrax among animals, which arose from natural causes, and there were cases where people contracted an intestinal form of this infection as a result of eating meat from cattle which was sold against the regulations established by the veterinary inspectorate.”19

The same day, after this statement, the conference approved a final declaration on the Biological Weapons Convention. The treaty was working, the member states declared. No one had filed any complaints about violations. Indeed, the word “violation” did not even appear in the final declaration. All the nations that signed the treaty reaffirmed their “strong determination for the sake of all mankind” to avoid biological weapons.20

A week later, the United States passed a secret message back to Moscow, saying that “reports available to us indicate a prolonged outbreak of pulmonary anthrax in Sverdlovsk, involving a large number of fatalities. Based on our experience, we would expect an outbreak of anthrax resulting from contaminated meat to have been of relatively short duration and to have resulted in only a small number of fatalities.”21

In Washington, the Central Intelligence Agency turned to experts, including Matthew Meselson, the Harvard molecular biologist who had earlier urged Nixon to outlaw biological weapons. Meselson got a call from Julian Hoptman, the CIA’s longtime analyst of biological weapons. For a week, Meselson stayed at Hoptman’s home, and, with secret clearances, worked at Hoptman’s office at CIA headquarters. They pored over the raw intelligence reports, but the evidence was ambiguous. Hoptman had located the practicing surgeon from Sverdlovsk mentioned in the DIA report, who had emigrated to Israel, and interviewed him. But other sources traveling through Sverdlovsk heard nothing about an epidemic. It turned out the report of an explosion was not correct, but there were many unanswered questions, especially about the diagnosis. In notes he made from that week, Meselson wrote, “The main technical question in my mind at this point concerns the diagnosis of respiratory anthrax.” Was the anthrax inhaled by the victims, which might point to biological weapons dispersed in an aerosol, or was it ingested by them, which could be explained by distribution of bad meat? Or was it some other respiratory disease altogether?

A related puzzle was why the cases continued for seven weeks. The textbooks Meselson consulted had suggested the incubation period for anthrax was a few days. If there was a single cloud of spores, there should have been a rapid fall-off of new cases. Instead, people kept getting sick for quite some time. In his work in Hoptman’s office, Meselson concluded that they needed to know much, much more before they could reach a conclusion. Where did the victims work when they were exposed? Where did they live? Which direction were the winds blowing? What would they learn if they plotted all the victims on a map, and then drew an ellipse from Compound 19—how many would be inside that ellipse? And what was going on at Compound 19? Did the local authorities respond with drug therapy, and if they did, was it effective? Why were there so many fatalities if they had drugs readily available? At this early stage, Meselson was cautious, and probing. Meselson also learned that a

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